来自北京大学的朱玉贤教授及其同事报道了二倍体雷蒙德氏棉花(Gossypium raimondii)的基因组草图。雷蒙德氏棉花是一种野生的南美洲棉,它的祖先被认为是异源四倍体商业棉陆地棉(Gossypium hirsutum)和海岛棉(Gossypium barbadense)其D亚基因组的贡献者。相关的研究论文于8月26日在线发表在《Nature Genetics》期刊上。

-2012年10月《自然-遗传》

中文翻译


【题目】科学家成功绘制二倍体雷蒙德氏棉花(Gossypium raimondii)的基因组草图 

【译文】本研究组已经对棉花(G. raimondii)的基因组进行测序并组装了其基因组草图,雷蒙德氏棉花(G. raimondii)的祖先是一种重要经济作物——产纤维棉种陆地棉(Gossypium hirsutum)和海岛棉(Gossypium barbadense)其D亚基因组的假定贡献物种。超过73%的已组装序列被瞄定到雷蒙德氏棉花的13条染色体上。雷蒙德氏棉花的基因组包含40976个蛋白编码基因,其中92.2%的基因得到转录组数据的进一步证实。研究发现了真双子叶植物基因组复制事件(染色体六倍体化)和发生在约一千三百万到二千万年前的棉花特有的全基因组复制事件。本研究在雷蒙德氏棉花中鉴定到2355个保守块,还发现约40%的平行进化同源基因存在于不止一个的保守块中,这表明雷蒙德氏棉花的基因组在进化过程中经历了大量的染色体重排。根据系统进化分析,本研究认为棉花和可可(Theobroma cacao)有可能是唯一真正具有棉酚生物合成CDN1基因家族的已测序植物物种。

英文原稿


[Title]: The draft genome of a diploid cotton Gossypium raimondii

[Authors]: Kunbo Wang, Zhiwen Wang, Fuguang Li, Wuwei Ye, Junyi Wang, Guoli Song, Zhen Yue, Lin Cong, Haihong Shang, Shilin Zhu, Changsong Zou, Qin Li, Youlu Yuan, Cairui Lu, Hengling Wei, Caiyun Gou, Zequn Zheng, Ye Yin, Xueyan Zhang, Kun Liu, Bo Wang, Chi Song, Nan Shi, Russell J Kohel, Richard G Percy, John Z Yu, Yu-Xian Zhu, Jun Wang & Shuxun Yu

[Abstract]: We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is the putative contributor of the D subgenome to the economically important fiber-producing cotton species Gossypium hirsutum and Gossypium barbadense. Over 73% of the assembled sequences were anchored on 13 G. raimondii chromosomes. The genome contains 40,976 protein-coding genes, with 92.2% of these further confirmed by transcriptome data. Evidence of the hexaploidization event shared by the eudicots as well as of a cotton-specific whole-genome duplication approximately 13–20 million years ago was observed. We identified 2,355 syntenic blocks in the G. raimondii genome, and we found that approximately 40% of the paralogous genes were present in more than 1 block, which suggests that this genome has undergone substantial chromosome rearrangement during its evolution. Cotton, and probably Theobroma cacao, are the only sequenced plant species that possess an authentic CDN1 gene family for gossypol biosynthesis, as revealed by phylogenetic analysis.

原文地址

http://www.nature.com/ng/journal/v44/n10/abs/ng.2371.html

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